Tag: Schizophrenia

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Assessing the validity of a self-reported clinical diagnosis of schizophrenia

ParticipantsStudy participants came from two clinically-ascertained Cardiff University cohorts, the National Centre for Mental Health (NCMH) and CardiffCOGS, and from the UK Biobank....

A systematic review and meta-analysis of nitric oxide-associated arginine metabolites in schizophrenia

Systematic searchWe initially identified 1398 studies, of which 1375 were excluded because they were either duplicates or irrelevant. After a full-text review of...

PET clinical study of novel antipsychotic LB-102 demonstrates unexpectedly prolonged dopamine receptor target engagement

This study was conducted at the Mallinckrodt Institute of Radiology (MIR) PET facility at Washington University School of Medicine (WUSM) in St. Louis...

Caudate nucleus volume in medicated and unmedicated patients with early- and adult-onset schizophrenia

Main analysisAdult patient analysisIn the bivariate analysis, patients with EOS were on average seven years younger (p < 0.001), had three years longer DOI (p < 0.001)...

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