Tag: Medicine/Public Health
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PET clinical study of novel antipsychotic LB-102 demonstrates unexpectedly prolonged dopamine receptor target engagement
This study was conducted at the Mallinckrodt Institute of Radiology (MIR) PET facility at Washington University School of Medicine (WUSM) in St. Louis...
Prevalence and incidence measures for schizophrenia among commercial health insurance and medicaid enrollees
Population characteristicsThe characteristics of the 2019 total population and 10 year continuously insured cohorts for MarketScan (N = 16,365,997 and n = 951,173, respectively) and Medicaid (N = 4,414,153...
Is game-based therapy effective for treating cognitive deficits in adults with schizophrenia? Evidence from a randomized controlled trial
The trial was a parallel group, efficacy trial of game-based therapy among chronic schizophrenia patients. The trial is registered at http://www.chictr.org.cn, identifier ChiCTR2100048403.ParticipantsEighty...
A systematic review of structural and functional magnetic resonance imaging studies on the neurobiology of depressive symptoms in schizophrenia spectrum disorders
Overview of study characteristicsOur initial search identified 5,765 potentially relevant studies, excluding duplicates. Following a review of titles and abstracts, 5570 studies were...
Functional phenotypes in schizophrenia spectrum disorders: defining the constructs and identifying biopsychosocial correlates using data-driven methods
ParticipantsAll participants were clinically stable adult outpatients with schizophrenia spectrum disorder (SSD) (Table 1) and provided written informed consent; all study protocols were...